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In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma
Di-peptides derived from the human host defense peptide lactoferricin were previously described to specifically interact with the negatively charged lipid phosphatidylserine exposed by cancer cells. In this study one further derivative, namely R-DIM-P-LF11-334 is shown to exhibit even increased canc...
Autores principales: | Riedl, Sabrina, Rinner, Beate, Schaider, Helmut, Liegl-Atzwanger, Bernadette, Meditz, Katharina, Preishuber-Pflügl, Julia, Grissenberger, Sarah, Lohner, Karl, Zweytick, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641092/ https://www.ncbi.nlm.nih.gov/pubmed/29069749 http://dx.doi.org/10.18632/oncotarget.17823 |
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