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AG488 as a therapy against gliomas
High-grade gliomas such as glioblastomas (GBM) present a deadly prognosis following diagnosis and very few effective treatment options. Here, we investigate if the small molecule AG488 can be an effective therapy against GBM with both anti-angiogenic as well as an anti-microtubule inhibiting modalit...
Autores principales: | Ziegler, Jadith, Bastian, Anja, Lerner, Megan, Bailey-Downs, Lora, Saunders, Debra, Smith, Nataliya, Sutton, Jake, Battiste, James D., Ihnat, Michael A., Gangjee, Aleem, Towner, Rheal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641093/ https://www.ncbi.nlm.nih.gov/pubmed/29069750 http://dx.doi.org/10.18632/oncotarget.18284 |
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