A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells

Prep1 is a homeodomain transcription factor belonging to the TALE protein family. Its overexpression affects glucose metabolism in several tissues. In particular, in skeletal muscle tissue the interaction of Prep1 with its cofactor p160 impairs GLUT4 expression and glucose uptake. In this study, we...

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Detalles Bibliográficos
Autores principales: Cimmino, Ilaria, Lorenzo, Virginia, Fiory, Francesca, Doti, Nunzianna, Ricci, Serena, Cabaro, Serena, Liotti, Antonietta, Vitagliano, Luigi, Longo, Michele, Miele, Claudia, Formisano, Pietro, Beguinot, Francesco, Ruvo, Menotti, Oriente, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641094/
https://www.ncbi.nlm.nih.gov/pubmed/29069751
http://dx.doi.org/10.18632/oncotarget.18286

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