Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth

The pathogenic role of the PHOX2B gene in neuroblastoma is indicated by heterozygous mutations in neuroblastoma patients and by gene overexpression in both neuroblastoma cell lines and tumor samples. PHOX2B encodes a transcription factor which is crucial for the correct development and differentiati...

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Detalles Bibliográficos
Autores principales: Zanni, Eleonora Di, Bianchi, Giovanna, Ravazzolo, Roberto, Raffaghello, Lizzia, Ceccherini, Isabella, Bachetti, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641117/
https://www.ncbi.nlm.nih.gov/pubmed/29069774
http://dx.doi.org/10.18632/oncotarget.19922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641117/
https://www.ncbi.nlm.nih.gov/pubmed/29069774
http://dx.doi.org/10.18632/oncotarget.19922

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