TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression

The Transducin-like enhancer of split 1 (TLE1) corepressor protein is overexpressed in human lung tumors and is a putative lung-specific oncogene. However, the molecular mechanism underlying its oncogenic function remains to be delineated. Here, we report an important role of TLE1 in promoting lung...

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Detalles Bibliográficos
Autores principales: Yao, Xin, Pham, Tri, Temple, Brandi, Gray, Selena, Cannon, Cornita, Hardy, Camry, Fletcher, Kamari, Ireland, Shubha Kale, Hossain, Ahamed, Chen, Renwei, Abdel-Mageed, Asim B., Biliran, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641126/
https://www.ncbi.nlm.nih.gov/pubmed/29069783
http://dx.doi.org/10.18632/oncotarget.19703

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