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Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer
Gefitinib showed response in phase II clinical trials and with better clinical response in lung cancer with activating mutations in the tyrosine kinase domain of the EGFR. Questions of toxicity and potential dosing regimens impede the use in a prevention setting. This study will provide scientific e...
Autores principales: | Zhang, Qi, Li, Ruichao, Chen, Xu, Lee, Sang Beom, Pan, Jing, Xiong, Donghai, Hu, Jiaqi, Miller, Mark Steven, Szabo, Eva, Lubet, Ronald A., Wang, Yian, You, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641144/ https://www.ncbi.nlm.nih.gov/pubmed/29069801 http://dx.doi.org/10.18632/oncotarget.19785 |
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