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Telomerase and drug resistance in cancer

It is well known that a decreased expression or inhibited activity of telomerase in cancer cells is accompanied by an increased sensitivity to some drugs (e.g., doxorubicin, cisplatin, or 5-fluorouracil). However, the mechanism of the resistance resulting from telomerase alteration remains elusive....

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Detalles Bibliográficos
Autores principales:	Lipinska, Natalia, Romaniuk, Aleksandra, Paszel-Jaworska, Anna, Toton, Ewa, Kopczynski, Przemyslaw, Rubis, Blazej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641272/ https://www.ncbi.nlm.nih.gov/pubmed/28623509 http://dx.doi.org/10.1007/s00018-017-2573-2

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