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Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development

Maintenance of genomic integrity is one of the critical features for proper neurodevelopment and inhibition of neurological diseases. The signals from both ATM and ATR to TP53 are well-known mechanisms to remove neural cells with DNA damage during neurogenesis. Here we examined the involvement of At...

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Detalles Bibliográficos
Autores principales: Kim, Jusik, Choi, Inseo, Lee, Youngsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641282/
https://www.ncbi.nlm.nih.gov/pubmed/28620865
http://dx.doi.org/10.1007/s00418-017-1591-3