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Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization

Molecular signal transmission in cell is very crucial for information exchange. How to understand its transmission mechanism has attracted many researchers. In this paper, we prove that signal transmission problem between neural tumor molecules and drug molecules can be achieved by synchronous contr...

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Detalles Bibliográficos
Autores principales: Zhou, Lingli, Shen, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641312/
https://www.ncbi.nlm.nih.gov/pubmed/29066966
http://dx.doi.org/10.3389/fncom.2017.00092
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author Zhou, Lingli
Shen, Jianwei
author_facet Zhou, Lingli
Shen, Jianwei
author_sort Zhou, Lingli
collection PubMed
description Molecular signal transmission in cell is very crucial for information exchange. How to understand its transmission mechanism has attracted many researchers. In this paper, we prove that signal transmission problem between neural tumor molecules and drug molecules can be achieved by synchronous control. To achieve our purpose, we derive the Fokker-Plank equation by using the Langevin equation and theory of random walk, this is a model which can express the concentration change of neural tumor molecules. Second, according to the biological character that vesicles in cell can be combined with cell membrane to release the cargo which plays a role of signal transmission, we preliminarily analyzed the mechanism of tumor-drug molecular interaction. Third, we propose the view of synchronous control which means the process of vesicle docking with their target membrane is a synchronization process, and we can achieve the precise treatment of disease by using synchronous control. We believe this synchronous control mechanism is reasonable and two examples are given to illustrate the correctness of our results obtained in this paper.
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spelling pubmed-56413122017-10-24 Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization Zhou, Lingli Shen, Jianwei Front Comput Neurosci Neuroscience Molecular signal transmission in cell is very crucial for information exchange. How to understand its transmission mechanism has attracted many researchers. In this paper, we prove that signal transmission problem between neural tumor molecules and drug molecules can be achieved by synchronous control. To achieve our purpose, we derive the Fokker-Plank equation by using the Langevin equation and theory of random walk, this is a model which can express the concentration change of neural tumor molecules. Second, according to the biological character that vesicles in cell can be combined with cell membrane to release the cargo which plays a role of signal transmission, we preliminarily analyzed the mechanism of tumor-drug molecular interaction. Third, we propose the view of synchronous control which means the process of vesicle docking with their target membrane is a synchronization process, and we can achieve the precise treatment of disease by using synchronous control. We believe this synchronous control mechanism is reasonable and two examples are given to illustrate the correctness of our results obtained in this paper. Frontiers Media S.A. 2017-10-10 /pmc/articles/PMC5641312/ /pubmed/29066966 http://dx.doi.org/10.3389/fncom.2017.00092 Text en Copyright © 2017 Zhou and Shen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Zhou, Lingli
Shen, Jianwei
Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title_full Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title_fullStr Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title_full_unstemmed Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title_short Signal Transmission of Biological Reaction-Diffusion System by Using Synchronization
title_sort signal transmission of biological reaction-diffusion system by using synchronization
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641312/
https://www.ncbi.nlm.nih.gov/pubmed/29066966
http://dx.doi.org/10.3389/fncom.2017.00092
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