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From Resistance to Sensitivity: Insights and Implications of Biphasic Modulation of Autophagy by Sunitinib

Sunitinib, a multityrosine kinase inhibitor, is currently the standard first-line therapy in metastatic renal cell carcinoma (mRCC) and is also used in treating patients with pancreatic neuroendocrine and imatinib-resistant gastrointestinal stromal tumors (GIST). Nevertheless, most patients eventual...

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Detalles Bibliográficos
Autores principales:	Abdel-Aziz, Amal Kamal, Abdel-Naim, Ashraf B., Shouman, Samia, Minucci, Saverio, Elgendy, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641351/ https://www.ncbi.nlm.nih.gov/pubmed/29066973 http://dx.doi.org/10.3389/fphar.2017.00718

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