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An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes

The ability to produce unlimited numbers of human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) harboring disease and patient-specific gene variants creates a new paradigm for modeling congenital heart diseases (CHDs) and predicting proarrhythmic liabilities of drug candidates. Ho...

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Detalles Bibliográficos
Autores principales:	McKeithan, Wesley L., Savchenko, Alex, Yu, Michael S., Cerignoli, Fabio, Bruyneel, Arne A. N., Price, Jeffery H., Colas, Alexandre R., Miller, Evan W., Cashman, John R., Mercola, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641590/ https://www.ncbi.nlm.nih.gov/pubmed/29075196 http://dx.doi.org/10.3389/fphys.2017.00766

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