Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA

OBJECTIVE: Functional investigation of novel gene/protein targets associated with adipocyte differentiation or function heavily relies on efficient and accessible tools to manipulate gene expression in adipocytes in vitro. Recent advances in gene-editing technologies such as CRISPR-Cas9 have not onl...

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Detalles Bibliográficos
Autores principales: Lundh, Morten, Pluciñska, Kaja, Isidor, Marie S., Petersen, Patricia S.S., Emanuelli, Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641601/
https://www.ncbi.nlm.nih.gov/pubmed/29031730
http://dx.doi.org/10.1016/j.molmet.2017.07.001

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