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ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

OBJECTIVE: Several members of the angiopoietin-like (ANGPTL) family of proteins, including ANGPTL3 and ANGPTL8, regulate lipoprotein lipase (LPL) activity. Deficiency in either ANGPTL3 or ANGPTL8 reduces plasma triglyceride levels and increases LPL activity, whereas overexpression of either protein...

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Detalles Bibliográficos
Autores principales: Chi, Xun, Britt, Emily C., Shows, Hannah W., Hjelmaas, Alexander J., Shetty, Shwetha K., Cushing, Emily M., Li, Wendy, Dou, Alex, Zhang, Ren, Davies, Brandon S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641604/
https://www.ncbi.nlm.nih.gov/pubmed/29031715
http://dx.doi.org/10.1016/j.molmet.2017.06.014

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