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Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia

Expression of the Ret receptor tyrosine kinase is a defining feature of enteric neurons. Its importance is underscored by the effects of its mutation in Hirschsprung disease, leading to absence of gut innervation and severe gastrointestinal symptoms. We report a new and physiologically significant s...

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Detalles Bibliográficos
Autores principales: Perea, Daniel, Guiu, Jordi, Hudry, Bruno, Konstantinidou, Chrysoula, Milona, Alexandra, Hadjieconomou, Dafni, Carroll, Thomas, Hoyer, Nina, Natarajan, Dipa, Kallijärvi, Jukka, Walker, James A, Soba, Peter, Thapar, Nikhil, Burns, Alan J, Jensen, Kim B, Miguel‐Aliaga, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641678/
https://www.ncbi.nlm.nih.gov/pubmed/28899900
http://dx.doi.org/10.15252/embj.201696247