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Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment

OBJECTIVE: Upon activation, G protein coupled receptors (GPCRs) associate with heterotrimeric G proteins at the plasma membrane to initiate second messenger signaling. Subsequently, the activated receptor experiences desensitization, internalization, and recycling back to the plasma membrane, or it...

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Detalles Bibliográficos
Autores principales:	Girada, Shravan Babu, Kuna, Ramya S., Bele, Shilpak, Zhu, Zhimeng, Chakravarthi, N.R., DiMarchi, Richard D., Mitra, Prasenjit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641683/ https://www.ncbi.nlm.nih.gov/pubmed/29031718 http://dx.doi.org/10.1016/j.molmet.2017.08.002

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