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Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

OBJECTIVE: Increased hepatic expression of dipeptidyl peptidase 4 (DPP4) is associated with non-alcoholic fatty liver disease (NAFLD). Whether this is causative for the development of NAFLD is not yet clarified. Here we investigate the effect of hepatic DPP4 overexpression on the development of live...

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Detalles Bibliográficos
Autores principales: Baumeier, Christian, Schlüter, Luisa, Saussenthaler, Sophie, Laeger, Thomas, Rödiger, Maria, Alaze, Stella Amelie, Fritsche, Louise, Häring, Hans-Ulrich, Stefan, Norbert, Fritsche, Andreas, Schwenk, Robert Wolfgang, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641684/
https://www.ncbi.nlm.nih.gov/pubmed/29031724
http://dx.doi.org/10.1016/j.molmet.2017.07.016

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