Snapin promotes HIV‐1 transmission from dendritic cells by dampening TLR8 signaling

HIV‐1 traffics through dendritic cells (DCs) en route to establishing a productive infection in T lymphocytes but fails to induce an innate immune response. Within DC endosomes, HIV‐1 somehow evades detection by the pattern‐recognition receptor (PRR) Toll‐like receptor 8 (TLR8). Using a phosphoprote...

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Detalles Bibliográficos
Autores principales: Khatamzas, Elham, Hipp, Madeleine Maria, Gaughan, Daniel, Pichulik, Tica, Leslie, Alasdair, Fernandes, Ricardo A, Muraro, Daniele, Booth, Sarah, Zausmer, Kieran, Sun, Mei‐Yi, Kessler, Benedikt, Rowland‐Jones, Sarah, Cerundolo, Vincenzo, Simmons, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641917/
https://www.ncbi.nlm.nih.gov/pubmed/28923824
http://dx.doi.org/10.15252/embj.201695364

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