Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

Amyloid β (Aβ) deposition in the brain is an early and invariable feature of Alzheimer’s disease (AD). The Aβ peptides are composed of about 40 amino acids and are generated from amyloid precursor proteins (APP), by β- and γ-secretases. The distribution of individual Aβ peptides in the brains of age...

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Detalles Bibliográficos
Autores principales: Kakuda, Nobuto, Miyasaka, Tomohiro, Iwasaki, Noriyuki, Nirasawa, Takashi, Wada-Kakuda, Satoko, Takahashi-Fujigasaki, Junko, Murayama, Shigeo, Ihara, Yasuo, Ikegawa, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641992/
https://www.ncbi.nlm.nih.gov/pubmed/29037261
http://dx.doi.org/10.1186/s40478-017-0477-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641992/
https://www.ncbi.nlm.nih.gov/pubmed/29037261
http://dx.doi.org/10.1186/s40478-017-0477-x

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