Cargando…

Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

Amyloid β (Aβ) deposition in the brain is an early and invariable feature of Alzheimer’s disease (AD). The Aβ peptides are composed of about 40 amino acids and are generated from amyloid precursor proteins (APP), by β- and γ-secretases. The distribution of individual Aβ peptides in the brains of age...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kakuda, Nobuto, Miyasaka, Tomohiro, Iwasaki, Noriyuki, Nirasawa, Takashi, Wada-Kakuda, Satoko, Takahashi-Fujigasaki, Junko, Murayama, Shigeo, Ihara, Yasuo, Ikegawa, Masaya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641992/ https://www.ncbi.nlm.nih.gov/pubmed/29037261 http://dx.doi.org/10.1186/s40478-017-0477-x

Ejemplares similares

Distribution of endogenous normal tau in the mouse brain
por: Kubo, Atsuko, et al.
Publicado: (2018)

The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives
por: Yoshimura, Rikuya, et al.
Publicado: (2023)

Switched Aβ43 generation in familial Alzheimer’s disease with presenilin 1 mutation
por: Kakuda, Nobuto, et al.
Publicado: (2021)

Chronological Profiling of Plasma Native Peptides after Hepatectomy in Pigs: Toward the Discovery of Human Biomarkers for Liver Regeneration
por: Iguchi, Kohta, et al.
Publicado: (2017)

Substrate ectodomain is critical for substrate preference and inhibition of γ-secretase
por: Funamoto, Satoru, et al.
Publicado: (2013)

Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions
por: Park, Hongsun, et al.
Publicado: (2022)

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease
por: Kakuda, Nobuto, et al.
Publicado: (2012)

Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo
por: Saito, Taro, et al.
Publicado: (2021)

The Homologous Carboxyl-Terminal Domains of Microtubule-Associated Protein 2 and TAU Induce Neuronal Dysfunction and Have Differential Fates in the Evolution of Neurofibrillary Tangles
por: Xie, Ce, et al.
Publicado: (2014)

Quantitative Assessment of Serine-8 Phosphorylated β-Amyloid Using MALDI-TOF Mass Spectrometry
por: Kuzin, Andrey A., et al.
Publicado: (2022)

Placenta Accreta Spectrum Disorder Complicated with Endometriosis: Systematic Review and Meta-Analysis
por: Matsuzaki, Shinya, et al.
Publicado: (2022)

Comparison of Vacuum MALDI and AP-MALDI Platforms for the Mass Spectrometry Imaging of Metabolites Involved in Salt Stress in Medicago truncatula
por: Keller, Caitlin, et al.
Publicado: (2018)

Reliability and Validity of Caregivers’ Fear of Falling Index When Caring for Home-Based Rehabilitation Patients With Fall-Related Fractures
por: Kakehi, Tomohiro, et al.
Publicado: (2023)

Imbalance in Fatty-Acid-Chain Length of Gangliosides Triggers Alzheimer Amyloid Deposition in the Precuneus
por: Oikawa, Naoto, et al.
Publicado: (2015)

Carbohydrate Antigen 19-9-Positive Gastric Adenocarcinoma: Autopsy Findings and Review of the Literature
por: Wang, Tan, et al.
Publicado: (2017)

The Effect of Tofogliflozin Treatment on Postprandial Glucose and Lipid Metabolism in Japanese Men With Type 2 Diabetes: A Pilot Study
por: Kakuda, Hirokazu, et al.
Publicado: (2017)

A Moldy Application of MALDI: MALDI-ToF Mass Spectrometry for Fungal Identification
por: Patel, Robin
Publicado: (2019)

Batch Effects in MALDI Mass Spectrometry Imaging
por: Balluff, Benjamin, et al.
Publicado: (2021)

Performance of MALDI–TOF Mass Spectrometry in the Philippines
por: Osa, Morichika, et al.
Publicado: (2021)

Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput assay and MALDI imaging mass spectrometry()
por: McClure, Richard A., et al.
Publicado: (2013)

Lipoma in the Corpus Callosum Presenting with Epileptic Seizures Associated with Expanding Perifocal Edema: A Case Report and Literature Review
por: Fuga, Michiyasu, et al.
Publicado: (2015)

Light and heavy chain deposition disease with focal amyloid deposition diagnosed with mass spectrometry: a case report
por: Shimamoto, Yuki, et al.
Publicado: (2023)

Localization of Flavan-3-ol Species in Peanut Testa by Mass Spectrometry Imaging
por: Enomoto, Hirofumi, et al.
Publicado: (2020)

Analysis of RNA cleavage by MALDI-TOF mass spectrometry
por: Joyner, Jeff C., et al.
Publicado: (2013)

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease
por: Hanrieder, Jörg, et al.
Publicado: (2012)

Rapid MALDI mass spectrometry imaging for surgical pathology
por: Basu, Sankha S., et al.
Publicado: (2019)

Advances in MALDI Mass Spectrometry in Clinical Diagnostic Applications
por: Ng, Eddy W. Y., et al.
Publicado: (2013)

Application of MALDI-TOF Mass Spectrometry in Clinical Virology
por: Camarasa, Cristina Gómez, et al.
Publicado: (2018)

MALDI-TOF Mass Spectrometry in Clinical Analysis and Research
por: Li, Dandan, et al.
Publicado: (2022)

MALDI-TOF Mass Spectrometry for interrogating ubiquitin enzymes
por: De Cesare, Virginia
Publicado: (2023)

MALDI-2 Mass Spectrometry for Synthetic Polymer Analysis
por: Molina-Millán, Lidia, et al.
Publicado: (2023)

MALDI Imaging Mass Spectrometry (MALDI-IMS)—Application of Spatial Proteomics for Ovarian Cancer Classification and Diagnosis
por: Gustafsson, Johan O. R., et al.
Publicado: (2011)

Validation of a novel automatic deposition of bacteria and yeasts on MALDI target for MALDI-TOF MS-based identification using MALDI Colonyst robot
por: Chudejova, Katerina, et al.
Publicado: (2017)

N-terminal peptide fragment constitutes core of amyloid deposition of serum amyloid A: An imaging mass spectrometry study
por: Shintani-Domoto, Yukako, et al.
Publicado: (2022)

A Case Report and Literature Review of Midtrimester Termination of Pregnancy Complicated by Placenta Previa and Placenta Accreta
por: Matsuzaki, Satoko, et al.
Publicado: (2014)

Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities
por: Matsuzaki, Shinya, et al.
Publicado: (2021)

An easy adjustment of instrument settings (‘Peak MALDI’) improves identification of organisms by MALDI-ToF mass spectrometry
por: Nellessen, Christopher M., et al.
Publicado: (2023)

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
por: Ritorto, Maria Stella, et al.
Publicado: (2014)

Susceptibility Testing of Bacteria Using Maldi-Tof Mass Spectrometry
por: Burckhardt, Irene, et al.
Publicado: (2018)

MALDI-TOF mass spectrometry for sub-typing of Streptococcus pneumoniae
por: Kann, Sivkheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e3448q9ggsfcvkurjbblbhb2s3