Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner

BACKGROUND: Improving the neuronal yield from in vitro cultivated neural progenitor cells (NPCs) is an essential challenge in transplantation therapy in neurological disorders. In this regard, Ascorbic acid (AA) is widely used to expand neurogenesis from NPCs in cultures although the mechanisms of i...

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Detalles Bibliográficos
Autores principales: Rharass, Tareck, Lantow, Margareta, Gbankoto, Adam, Weiss, Dieter G., Panáková, Daniela, Lucas, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641995/
https://www.ncbi.nlm.nih.gov/pubmed/29037191
http://dx.doi.org/10.1186/s12929-017-0385-1

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