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Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
Microglia, the tissue-resident macrophages in the brain, are damage sensors that react to nearly any perturbation, including neurodegenerative diseases such as Alzheimer’s disease (AD). Here, using single-cell RNA sequencing, we determined the transcriptome of more than 1,600 individual microglia ce...
Autores principales: | Mathys, Hansruedi, Adaikkan, Chinnakkaruppan, Gao, Fan, Young, Jennie Z., Manet, Elodie, Hemberg, Martin, De Jager, Philip L., Ransohoff, Richard M., Regev, Aviv, Tsai, Li-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642107/ https://www.ncbi.nlm.nih.gov/pubmed/29020624 http://dx.doi.org/10.1016/j.celrep.2017.09.039 |
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