Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus

Cephalosporins are a commonly used class of antibiotics in various types of infections. Cefepime, a fourth-generation cephalosporin, has been reported to cause neurotoxicity, which can present itself as varied manifestations. Nonconvulsive status epilepticus (NCSE) is a rare manifestation of this ne...

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Autores principales: Anuhya, Vinayaka, Kunder, Sushil Kiran, Madhyastha, Sharath, Nayak, Veena, Acharya, Raviraja V., Ramamoorthi, Kusugodlu, Arivazhahan, Avinash, Gangula, Rahul Sai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642132/
https://www.ncbi.nlm.nih.gov/pubmed/29081627
http://dx.doi.org/10.4103/jpp.JPP_64_17
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author Anuhya, Vinayaka
Kunder, Sushil Kiran
Madhyastha, Sharath
Nayak, Veena
Acharya, Raviraja V.
Ramamoorthi, Kusugodlu
Arivazhahan, Avinash
Gangula, Rahul Sai
author_facet Anuhya, Vinayaka
Kunder, Sushil Kiran
Madhyastha, Sharath
Nayak, Veena
Acharya, Raviraja V.
Ramamoorthi, Kusugodlu
Arivazhahan, Avinash
Gangula, Rahul Sai
author_sort Anuhya, Vinayaka
collection PubMed
description Cephalosporins are a commonly used class of antibiotics in various types of infections. Cefepime, a fourth-generation cephalosporin, has been reported to cause neurotoxicity, which can present itself as varied manifestations. Nonconvulsive status epilepticus (NCSE) is a rare manifestation of this neurotoxicity. This condition often proves difficult to diagnose because it is chiefly an electroencephalogram-based diagnosis. The authors report a case of cefepime-induced NCSE in a 57-year-old female patient with compromised renal status.
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spelling pubmed-56421322017-10-27 Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus Anuhya, Vinayaka Kunder, Sushil Kiran Madhyastha, Sharath Nayak, Veena Acharya, Raviraja V. Ramamoorthi, Kusugodlu Arivazhahan, Avinash Gangula, Rahul Sai J Pharmacol Pharmacother Case Report Cephalosporins are a commonly used class of antibiotics in various types of infections. Cefepime, a fourth-generation cephalosporin, has been reported to cause neurotoxicity, which can present itself as varied manifestations. Nonconvulsive status epilepticus (NCSE) is a rare manifestation of this neurotoxicity. This condition often proves difficult to diagnose because it is chiefly an electroencephalogram-based diagnosis. The authors report a case of cefepime-induced NCSE in a 57-year-old female patient with compromised renal status. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5642132/ /pubmed/29081627 http://dx.doi.org/10.4103/jpp.JPP_64_17 Text en Copyright: © 2017 Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Anuhya, Vinayaka
Kunder, Sushil Kiran
Madhyastha, Sharath
Nayak, Veena
Acharya, Raviraja V.
Ramamoorthi, Kusugodlu
Arivazhahan, Avinash
Gangula, Rahul Sai
Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title_full Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title_fullStr Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title_full_unstemmed Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title_short Looking beyond the Obvious: Cefepime-induced Nonconvulsive Status Epilepticus
title_sort looking beyond the obvious: cefepime-induced nonconvulsive status epilepticus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642132/
https://www.ncbi.nlm.nih.gov/pubmed/29081627
http://dx.doi.org/10.4103/jpp.JPP_64_17
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