Cargando…

Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity

This commentary focuses on potential molecular mechanisms related to the dysfunctional synaptic plasticity that is associated with neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease. Specifically, we focus on the role of striatal-enriched protein tyrosine phosphatase (ST...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lombroso, Paul J., Ogren, Marilee, Kurup, Pradeep, Nairn, Angus C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642311/ https://www.ncbi.nlm.nih.gov/pubmed/29098072 http://dx.doi.org/10.12688/f1000research.8571.1

Ejemplares similares

Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function
por: Kamceva, Marija, et al.
Publicado: (2016)

The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition
por: Fitzpatrick, Christopher James, et al.
Publicado: (2011)

Striatal-Enriched Protein Tyrosine Phosphatase Controls Responses to Aversive Stimuli: Implication for Ethanol Drinking
por: Legastelois, Rémi, et al.
Publicado: (2015)

Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases
por: Tjin, Caroline Chandra, et al.
Publicado: (2017)

Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)
por: Lambert, Lester J, et al.
Publicado: (2021)

Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase
por: Blázquez, Gloria, et al.
Publicado: (2019)

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease
por: Xu, Jian, et al.
Publicado: (2014)

Endocannabinoid–Dopamine Interactions in Striatal Synaptic Plasticity
por: Mathur, Brian N., et al.
Publicado: (2012)

The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications
por: Carty, N C, et al.
Publicado: (2012)

Regulation of STEP(61) and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity
por: Jang, Sung-Soo, et al.
Publicado: (2015)

Insight into the Role of the STriatal-Enriched Protein Tyrosine Phosphatase (STEP) in A(2A) Receptor-Mediated Effects in the Central Nervous System
por: Domenici, Maria Rosaria, et al.
Publicado: (2021)

Reelin Regulates Neuronal Excitability through Striatal-Enriched Protein Tyrosine Phosphatase (STEP(61)) and Calcium Permeable AMPARs in an NMDAR-Dependent Manner
por: Durakoglugil, Murat S., et al.
Publicado: (2021)

Functional repertoire of protein kinases and phosphatases in synaptic plasticity and associated neurological disorders
por: Khan, Raheel, et al.
Publicado: (2020)

A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
por: Nakano, Takashi, et al.
Publicado: (2010)

Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity
por: Urakubo, Hidetoshi, et al.
Publicado: (2020)

A Common STEP in the Synaptic Pathology of Diverse Neuropsychiatric Disorders
por: Johnson, Micah A., et al.
Publicado: (2012)

Environmental enrichment shapes striatal spike-timing-dependent plasticity in vivo
por: Morera-Herreras, Teresa, et al.
Publicado: (2019)

Protein Kinase C-Dependent Dephosphorylation of Tyrosine Hydroxylase Requires the B56δ Heterotrimeric Form of Protein Phosphatase 2A
por: Ahn, Jung-Hyuck, et al.
Publicado: (2011)

Exosomes as Emerging Biomarker Tools in Neurodegenerative and Neuropsychiatric Disorders—A Proteomics Perspective
por: Mathew, Boby, et al.
Publicado: (2021)

Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease
por: Kim, Anya, et al.
Publicado: (2020)

Synaptic Effects of Palmitoylethanolamide in Neurodegenerative Disorders
por: Assogna, Martina, et al.
Publicado: (2022)

Environmental Enrichment Upregulates Striatal Synaptic Vesicle-Associated Proteins and Improves Motor Function
por: Song, Suk-Young, et al.
Publicado: (2018)

Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative Disorders
por: Brzdak, Patrycja, et al.
Publicado: (2017)

Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal development
por: Lee, Jae-Ran
Publicado: (2015)

The receptor protein tyrosine phosphatase CLR-1 is required for synaptic partner recognition
por: Varshney, Aruna, et al.
Publicado: (2018)

Acute and chronic effects by nicotine on striatal neurotransmission and synaptic plasticity in the female rat brain
por: Lucente, Erika, et al.
Publicado: (2023)

Friend or Foe? The Varied Faces of Homeostatic Synaptic Plasticity in Neurodegenerative Disease
por: Taylor, Henry B. C., et al.
Publicado: (2021)

Striatal Involvement in Neurodegenerative Langerhans Cell Histiocytosis
por: de Haan, Sven, et al.
Publicado: (2019)

Signaling Pathways Involved in Striatal Synaptic Plasticity are Sensitive to Temporal Pattern and Exhibit Spatial Specificity
por: Kim, BoHung, et al.
Publicado: (2013)

Striatal synaptic adaptations in Parkinson’s disease
por: Shen, Weixing, et al.
Publicado: (2022)

Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission
por: Foley, Karl, et al.
Publicado: (2022)

Recurrent Implication of Striatal Cholinergic Interneurons in a Range of Neurodevelopmental, Neurodegenerative, and Neuropsychiatric Disorders
por: Poppi, Lauren A., et al.
Publicado: (2021)

A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice
por: Kurz, Alexander, et al.
Publicado: (2010)

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease
por: Kolodziejczyk, Karolina, et al.
Publicado: (2014)

CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors
por: Crittenden, Jill R., et al.
Publicado: (2021)

Intensive exercise ameliorates motor and cognitive symptoms in experimental Parkinson’s disease restoring striatal synaptic plasticity
por: Marino, Gioia, et al.
Publicado: (2023)

Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
por: Pardo, Mònica, et al.
Publicado: (2023)

Lactate Metabolism, Signaling, and Function in Brain Development, Synaptic Plasticity, Angiogenesis, and Neurodegenerative Diseases
por: Wu, Anika, et al.
Publicado: (2023)

SH2 domain‐containing protein tyrosine phosphatase‐2 is enriched in eyelid specimens of rosacea
por: Chebolu, Apoorv, et al.
Publicado: (2022)

Beyond the Dopamine Receptor: Regulation and Roles of Serine/Threonine Protein Phosphatases
por: Walaas, Sven Ivar, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_f25k81eb7kqniqj80m2pn8ttcs