Empirical comparison of reduced representation bisulfite sequencing and Infinium BeadChip reproducibility and coverage of DNA methylation in humans

We empirically examined the strengths and weaknesses of two human genome-wide DNA methylation platforms: rapid multiplexed reduced representation bisulfite sequencing and Illumina’s Infinium BeadChip. Rapid multiplexed reduced representation bisulfite sequencing required less input DNA, offered more...

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Detalles Bibliográficos
Autores principales: Carmona, Juan J., Accomando, William P., Binder, Alexandra M., Hutchinson, John N., Pantano, Lorena, Izzi, Benedetta, Just, Allan C., Lin, Xihong, Schwartz, Joel, Vokonas, Pantel S., Amr, Sami S., Baccarelli, Andrea A., Michels, Karin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642382/
https://www.ncbi.nlm.nih.gov/pubmed/29263828
http://dx.doi.org/10.1038/s41525-017-0012-9

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