Suppression of tumor-derived Semaphorin 7A and genetic ablation of host-derived Semaphorin 7A impairs tumor progression in a murine model of advanced breast carcinoma

Solid tumors can generate a plethora of neurogenesis-related molecules that enhance their growth and metastasis. Among them, we have identified axonal guidance molecule Semaphorin 7A (SEMA7A) in breast cancer. The goal of this study was to determine the therapeutic effect of suppressing SEMA7A level...

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Detalles Bibliográficos
Autores principales: Garcia-Areas, R., Libreros, S., Simoes, M., Castro-Silva, C., Gazaniga, N., Amat, S., Jaczewska, J., Keating, P., Schilling, K., Brito, M., Wojcikiewicz, E.P., Iragavarpu-Charyulu, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642386/
https://www.ncbi.nlm.nih.gov/pubmed/29048670
http://dx.doi.org/10.3892/ijo.2017.4144

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