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Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)
Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic reprogramming to adapt to the tumor microenvironment and survive host defense or therapeutic insults. Intra-tumor heter...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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D.A. Spandidos
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642388/ https://www.ncbi.nlm.nih.gov/pubmed/29048660 http://dx.doi.org/10.3892/ijo.2017.4129 |