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Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia

There is substantial evidence that early growth response-1 (Egr1) gene, a zinc-finger transcription factor, behaves as a tumor suppressor in leukemia. This includes reports from this laboratory that constitutive Egr1 overrides leukemia conferred by deregulated c-Myc or E2F-1 in the M1 myeloid leukem...

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Detalles Bibliográficos
Autores principales:	Maifrede, Silvia, Magimaidas, Andrew, Sha, Xiaojin, Mukherjee, Kaushiki, Liebermann, Dan A., Hoffman, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642478/ https://www.ncbi.nlm.nih.gov/pubmed/29050203 http://dx.doi.org/10.18632/oncotarget.20612

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