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Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state
A yeast culture grown in a nutrient-rich medium initially containing 2% glucose is not limited in calorie supply. When yeast cells cultured in this medium consume glucose, they undergo cell cycle arrest at a checkpoint in late G1 and differentiate into quiescent and non-quiescent cell populations. S...
Autores principales: | Leonov, Anna, Feldman, Rachel, Piano, Amanda, Arlia-Ciommo, Anthony, Lutchman, Vicky, Ahmadi, Masoumeh, Elsaser, Sarah, Fakim, Hana, Heshmati-Moghaddam, Mahdi, Hussain, Asimah, Orfali, Sandra, Rajen, Harshvardhan, Roofigari-Esfahani, Negar, Rosanelli, Leana, Titorenko, Vladimir I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642482/ https://www.ncbi.nlm.nih.gov/pubmed/29050207 http://dx.doi.org/10.18632/oncotarget.20614 |
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