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Recombination activating gene-2(null) severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently

This study comparatively investigated the transcriptional, physiological, and phenotypic differences of the immune disorder between severe combined immunodeficient (SCID) mouse and pig models. We discovered that the recombination activating gene-2 (Rag-2) SCID mice, but not RAG-2 SCID pigs, showed i...

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Detalles Bibliográficos
Autores principales:	Choi, Yun-Jung, Kim, EunSu, Reza, Abu Musa Md Talimur, Hong, Kwonho, Song, Hyuk, Park, Chankyu, Cho, Seong-Keun, Lee, Kiho, Prather, Randall S., Kim, Jin-Hoi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642487/ https://www.ncbi.nlm.nih.gov/pubmed/29050212 http://dx.doi.org/10.18632/oncotarget.20626

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