Cargando…
Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies
Alzheimer´s disease (AD) is characterized by progressive dementia, initially presenting olfactory dysfunction. Despite the olfactory bulb (OB) is the first central structure of the olfactory pathway, we lack a complete molecular characterization of the transcriptional events that occurs in this olfa...
Autores principales: | Lachen-Montes, Mercedes, Zelaya, María Victoria, Segura, Víctor, Fernández-Irigoyen, Joaquín, Santamaría, Enrique |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642507/ https://www.ncbi.nlm.nih.gov/pubmed/29050232 http://dx.doi.org/10.18632/oncotarget.18193 |
Ejemplares similares
-
Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach
por: Cartas-Cejudo, Paz, et al.
Publicado: (2021) -
Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease
por: Lachen-Montes, Mercedes, et al.
Publicado: (2019) -
Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression
por: Lachén-Montes, Mercedes, et al.
Publicado: (2017) -
Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis
por: Lachén-Montes, Mercedes, et al.
Publicado: (2020) -
Olfactory Bulb Proteomics Reveals Widespread Proteostatic Disturbances in Mixed Dementia and Guides for Potential Serum Biomarkers to Discriminate Alzheimer Disease and Mixed Dementia Phenotypes
por: Lachén-Montes, Mercedes, et al.
Publicado: (2021)