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Modulation of the Nur77-Bcl-2 apoptotic pathway by p38α MAPK
Orphan nuclear receptor Nur77 promotes apoptosis by targeting mitochondria through interaction with Bcl-2, an event that converts Bcl-2 from a survival to killer. However, how the Nur77-Bcl-2 apoptotic pathway is regulated remains largely unknown. In this study, we examined the regulation of the Nur...
Autores principales: | Liu, Jie, Wang, Guang-Hui, Duan, Ying-Hui, Dai, Yi, Bao, Yuzhou, Hu, Mengjie, Zhou, Yu-Qi, Li, Mingyu, Jiang, Fuquan, Zhou, Hu, Yao, Xin-Sheng, Zhang, Xiao-Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642512/ https://www.ncbi.nlm.nih.gov/pubmed/29050237 http://dx.doi.org/10.18632/oncotarget.19227 |
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