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Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. Increasing evidence showed that microRNAs (miRNAs) play an important role in the PTC progression. In our study, the result showed that let-7a is significantly downregulated in PTC tissues and thyroid cancer cell lines. Overex...

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Detalles Bibliográficos
Autores principales: Zhou, Bin, Shan, Hailin, Su, Ying, Xia, Kai, Zou, Runlong, Shao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642513/
https://www.ncbi.nlm.nih.gov/pubmed/29050238
http://dx.doi.org/10.18632/oncotarget.19261