Sesquiterpene binding Gly-Leu-Ser/Lys-“co-adaptation pocket” to inhibit lung cancer cell epithelial–mesenchymal transition

Sesquiterpene lactones (SL) have a wide range of applications in anti-tumor and anti-inflammatory therapy. However, the pharmacological mechanism of such substances is not clear. In this study, parthenolide (PTL) was used as an example to explore the anti-tumor effect of natural molecules and their...

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Detalles Bibliográficos
Autores principales: Ai, Xiao-Yu, Zhang, Heng, Gao, Shao-Yan, Qin, Yuan, Zhong, Wei-Long, Gu, Ju, Li, Meng, Qiao, Kai-Liang, Tian, Qin, Cui, Zhan-Hong, Yang, Jia-Huan, Bi, Zhun, Xiao, Ting, Chen, Shuang, Liu, Hui-Juan, Zhou, Hong-Gang, Sun, Tao, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642546/
https://www.ncbi.nlm.nih.gov/pubmed/29050271
http://dx.doi.org/10.18632/oncotarget.19599

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