GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition

Cancer stem cells (CSCs) have been identified to exert tumor-initiating ability, resulting in the recurrence, metastasis and chemoresistance of oral squamous cell carcinomas. In the present study, we showed that GMI, an immunomodulatory protein from Ganoderma microsporum, induc ed a cytotoxic effect...

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Detalles Bibliográficos
Autores principales: Wang, Tung Yuan, Yu, Cheng-Chia, Hsieh, Pei-Ling, Liao, Yi-Wen, Yu, Chuan-Hang, Chou, Ming-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642565/
https://www.ncbi.nlm.nih.gov/pubmed/29050290
http://dx.doi.org/10.18632/oncotarget.19711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642565/
https://www.ncbi.nlm.nih.gov/pubmed/29050290
http://dx.doi.org/10.18632/oncotarget.19711

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