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MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury

Oxidative stress and neuroinflammation are the key factors leading to secondary brain injury after intracerebral hemorrhage (ICH). We investigated the effects of miR-27b, an oxidative stress-responsive microRNA, on ICH-induced brain injury in rats. The ICH model was induced by intracerebral injectio...

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Detalles Bibliográficos
Autores principales: Xu, Wenzhe, Li, Feng, Liu, Zhiguo, Xu, Zhenkuan, Sun, Bin, Cao, Jingwei, Liu, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642585/
https://www.ncbi.nlm.nih.gov/pubmed/29050310
http://dx.doi.org/10.18632/oncotarget.19974