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MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury
Oxidative stress and neuroinflammation are the key factors leading to secondary brain injury after intracerebral hemorrhage (ICH). We investigated the effects of miR-27b, an oxidative stress-responsive microRNA, on ICH-induced brain injury in rats. The ICH model was induced by intracerebral injectio...
Autores principales: | Xu, Wenzhe, Li, Feng, Liu, Zhiguo, Xu, Zhenkuan, Sun, Bin, Cao, Jingwei, Liu, Yuguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642585/ https://www.ncbi.nlm.nih.gov/pubmed/29050310 http://dx.doi.org/10.18632/oncotarget.19974 |
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