Cargando…

Pharmacokinetics and drug-drug interaction between enalapril, enalaprilat and felodipine extended release (ER) in healthy subjects

Since angiotensin-converting enzyme (ACE) inhibitors and calcium antagonists have complimentary mechanisms of action, enalapril, an ACE inhibitor, is used in combination with felodipine, a vascular selective dihydropyridine calcium antagonist, for the treatment of hypertension. The present study was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Dai, Xu, Sumei, Wang, Yulu, Li, Dan, Li, Xiaomin, Pan, Jing, Xu, Pingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642591/ https://www.ncbi.nlm.nih.gov/pubmed/29050316 http://dx.doi.org/10.18632/oncotarget.19984

Ejemplares similares

Clinical Pharmacokinetics of Enalapril and Enalaprilat in Pediatric Patients—A Systematic Review
por: Faisal, Muhammad, et al.
Publicado: (2021)

LC–MS/MS assay for quantitation of enalapril and enalaprilat in plasma for bioequivalence study in Indian subjects
por: Halder, Dhiman, et al.
Publicado: (2017)

Enalapril and Enalaprilat Pharmacokinetics in Children with Heart Failure Due to Dilated Cardiomyopathy and Congestive Heart Failure after Administration of an Orodispersible Enalapril Minitablet (LENA-Studies)
por: Laeer, Stephanie, et al.
Publicado: (2022)

Simultaneous Semi-Mechanistic Population Pharmacokinetic Modeling Analysis of Enalapril and Enalaprilat Serum and Urine Concentrations From Child Appropriate Orodispersible Minitablets
por: Faisal, Muhammad, et al.
Publicado: (2019)

Nanovesicles for transdermal delivery of felodipine: Development, characterization, and pharmacokinetics
por: Yusuf, Mohd, et al.
Publicado: (2014)

A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling
por: Fuhr, Laura Maria, et al.
Publicado: (2022)

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
por: Siddiqi, Farah H., et al.
Publicado: (2019)

The Difference in Pharmacokinetics and Pharmacodynamics between Extended-Release Fluvastatin and Immediate-Release Fluvastatin in Healthy Chinese Subjects
por: Xu, H. R., et al.
Publicado: (2012)

Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug
por: Salem, Farzaneh, et al.
Publicado: (2023)

Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
por: Siddiqi, Farah H., et al.
Publicado: (2019)

Identification of Structural Features for the Inhibition of OAT3-Mediated Uptake of Enalaprilat by Selected Drugs and Flavonoids
por: Ni, Yao, et al.
Publicado: (2020)

The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
por: Dahlgren, David, et al.
Publicado: (2020)

Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
por: Dahlgren, David, et al.
Publicado: (2021)

Gingival Enlargement Induced by Felodipine Resolves with a Conventional Periodontal Treatment and Drug Modification
por: Khzam, Nabil, et al.
Publicado: (2016)

In Silico, Experimental, Mechanistic Model for Extended-Release Felodipine Disposition Exhibiting Complex Absorption and a Highly Variable Food Interaction
por: Kim, Sean H. J., et al.
Publicado: (2014)

Sample Preparation and Extraction in Small Sample Volumes Suitable for Pediatric Clinical Studies: Challenges, Advances, and Experiences of a Bioanalytical HPLC-MS/MS Method Validation Using Enalapril and Enalaprilat
por: Burckhardt, Bjoern B., et al.
Publicado: (2015)

Development of a reservoir type prolonged release system with felodipine via simplex methodology
por: IOVANOV, RAREŞ IULIU, et al.
Publicado: (2016)

TRIB3 rs6037475 is a potential biomarker for predicting felodipine drug response in Chinese patients with hypertension
por: He, Fazhong, et al.
Publicado: (2020)

Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule
por: Smeets, Nori J. L., et al.
Publicado: (2020)

Effects of enalaprilat sodium on plasma NTproANP and NTproBNP levels in healthy volunteers
por: Heringlake, M, et al.
Publicado: (2006)

Effect of felodipine on indomethacin-induced gastric ulcers in rats
por: Akbaş, Nergis, et al.
Publicado: (2023)

Intravenous enalaprilat for treatment of acute hypertensive heart failure in the emergency department
por: Ayaz, Syed Imran, et al.
Publicado: (2016)

Randomized pharmacokinetic and drug–drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects
por: Das, Shampa, et al.
Publicado: (2015)

Hot-Melt Extrusion of the Thermo-Sensitive Peptidomimetic Drug Enalapril Maleate
por: Hoffmann, Lena, et al.
Publicado: (2022)

In-silico drug repurposing study: Amprenavir, enalaprilat, and plerixafor, potential drugs for destabilizing the SARS-CoV-2 S-protein-angiotensin-converting enzyme 2 complex
por: Buitrón-González, Ivonne, et al.
Publicado: (2021)

The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension
por: Ikonnikova, Anna, et al.
Publicado: (2022)

Exploring molecular reorientations in amorphous and recrystallized felodipine at the microscopic level
por: Pajzderska, A., et al.
Publicado: (2020)

Controlled Release of Felodipine from 3D-Printed Tablets with Constant Surface Area: Influence of Surface Geometry
por: Thanawuth, Kasitpong, et al.
Publicado: (2023)

Pharmacokinetics of Coadministration of Guanfacine Extended Release and Methylphenidate Extended Release
por: Roesch, Benno, et al.
Publicado: (2013)

Enhancement of the Solubility of BS Class II Drugs with MOF and MOF/GO Composite Materials: Case Studies of Felodipine, Ketoprofen and Ibuprofen
por: Han, Jinyang, et al.
Publicado: (2023)

Evaluation of pharmacokinetic drug-drug interaction between tegoprazan and clarithromycin in healthy subjects
por: Oh, Minkyung, et al.
Publicado: (2023)

Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects
por: Desai, Amit, et al.
Publicado: (2016)

Pharmacokinetic Drug‐Drug Interaction Study of Omecamtiv Mecarbil With Amiodarone and Digoxin in Healthy Subjects
por: Trivedi, Ashit, et al.
Publicado: (2021)

SUN-LB47 Extended Release Octreotide Pharmacokinetics in Healthy Subjects After Subcutaneous Injection of MTD201
por: Seaman, Paul, et al.
Publicado: (2020)

Population Pharmacokinetics of Upadacitinib Using the Immediate-Release and Extended-Release Formulations in Healthy Subjects and Subjects with Rheumatoid Arthritis: Analyses of Phase I–III Clinical Trials
por: Klünder, Ben, et al.
Publicado: (2019)

Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics
por: Faisal, Muhammad, et al.
Publicado: (2019)

Protective and therapeutic effect of felodipine against bleomycin-induced pulmonary fibrosis in mice
por: Tanaka, Ken-ichiro, et al.
Publicado: (2017)

Felodipine Determination by a CdTe Quantum Dot-Based Fluorescent Probe
por: Lv, Yuguang, et al.
Publicado: (2022)

CONTROLLED RELEASE MATRIX UNCOATED TABLETS OF ENALAPRIL MALEATE USING HPMC ALONE
por: Nair, Anroop B., et al.
Publicado: (2010)

Pharmacokinetics of immediate release, extended release, and gastric retentive gabapentin formulations in healthy adults
por: Swearingen, Dennis, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ak3juhnt5sa4rmcrtu957600qm