Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Novel therapies for neuroendocrine (NE) cancers are desperately needed as they frequently present as metastatic disease and cause debilitating symptoms by secreting excessive hormones. Induction of Notch isoforms has a tumor suppressive effect in NE cancer cell lines, and we have observed that histo...

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Detalles Bibliográficos
Autores principales: Jang, Samuel, Janssen, Andrew, Aburjania, Zviadi, Robers, Matthew B., Harrison, April, Dammalapati, Ajitha, Cheng, Yi-Qiang, Chen, Herbert, Jaskula-Sztul, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642598/
https://www.ncbi.nlm.nih.gov/pubmed/29050323
http://dx.doi.org/10.18632/oncotarget.19993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642598/
https://www.ncbi.nlm.nih.gov/pubmed/29050323
http://dx.doi.org/10.18632/oncotarget.19993

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