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The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) have been established as the standard therapy for EGFR-sensitizing mutant advanced non-small-cell lung cancer (NSCLC). However, patients ultimately develop resistance to these drugs. There are several mechanisms of both primary a...

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Detalles Bibliográficos
Autores principales:	Zhong, Wen-Zhao, Zhou, Qing, Wu, Yi-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642641/ https://www.ncbi.nlm.nih.gov/pubmed/29050366 http://dx.doi.org/10.18632/oncotarget.20311

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