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An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma

PURPOSE: To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. SETTING: University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. DESIGN: Nonrandomized single-center retrospective chart review. METHODS: Adult open-angle gl...

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Autores principales: Khaimi, Mahmoud A., Dvorak, Justin D., Ding, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642877/
https://www.ncbi.nlm.nih.gov/pubmed/29098083
http://dx.doi.org/10.1155/2017/2904272
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author Khaimi, Mahmoud A.
Dvorak, Justin D.
Ding, Kai
author_facet Khaimi, Mahmoud A.
Dvorak, Justin D.
Ding, Kai
author_sort Khaimi, Mahmoud A.
collection PubMed
description PURPOSE: To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. SETTING: University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. DESIGN: Nonrandomized single-center retrospective chart review. METHODS: Adult open-angle glaucoma eyes underwent canaloplasty or combined cataract-canaloplasty surgery. A tensioning suture was placed into Schlemm's canal in all eyes. Primary endpoints included the mean IOP and mean number of glaucoma medications at each follow-up visit. Secondary endpoints included visual acuity and surgical/postsurgical complications. RESULTS: The study cohort included 277 eyes (mean age, 72.8 years). Overall, the mean baseline IOP of 19.7 mmHg was reduced to 14.3 mmHg,14.0 mmHg, and 15.2 mmHg at 1, 2, and 3 years, respectively (p < 0.001). The average medicine use was reduced from 2.1 preoperatively to 0.4 at 12 months, and 0.5 and 0.6 at two and three years, respectively (p < 0.001). The frequency of surgical and postsurgical complications was low with no serious adverse events recorded. CONCLUSION: Canaloplasty was safe and effective in achieving long-term IOP reductions and reduced dependence on antiglaucoma medications.
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spelling pubmed-56428772017-11-02 An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma Khaimi, Mahmoud A. Dvorak, Justin D. Ding, Kai J Ophthalmol Research Article PURPOSE: To report 3-year results investigating the safety and efficacy of canaloplasty for open-angle glaucoma. SETTING: University of Oklahoma, Dean McGee Eye Institute, Oklahoma, United States of America. DESIGN: Nonrandomized single-center retrospective chart review. METHODS: Adult open-angle glaucoma eyes underwent canaloplasty or combined cataract-canaloplasty surgery. A tensioning suture was placed into Schlemm's canal in all eyes. Primary endpoints included the mean IOP and mean number of glaucoma medications at each follow-up visit. Secondary endpoints included visual acuity and surgical/postsurgical complications. RESULTS: The study cohort included 277 eyes (mean age, 72.8 years). Overall, the mean baseline IOP of 19.7 mmHg was reduced to 14.3 mmHg,14.0 mmHg, and 15.2 mmHg at 1, 2, and 3 years, respectively (p < 0.001). The average medicine use was reduced from 2.1 preoperatively to 0.4 at 12 months, and 0.5 and 0.6 at two and three years, respectively (p < 0.001). The frequency of surgical and postsurgical complications was low with no serious adverse events recorded. CONCLUSION: Canaloplasty was safe and effective in achieving long-term IOP reductions and reduced dependence on antiglaucoma medications. Hindawi 2017 2017-09-29 /pmc/articles/PMC5642877/ /pubmed/29098083 http://dx.doi.org/10.1155/2017/2904272 Text en Copyright © 2017 Mahmoud A. Khaimi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khaimi, Mahmoud A.
Dvorak, Justin D.
Ding, Kai
An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_full An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_fullStr An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_full_unstemmed An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_short An Analysis of 3-Year Outcomes Following Canaloplasty for the Treatment of Open-Angle Glaucoma
title_sort analysis of 3-year outcomes following canaloplasty for the treatment of open-angle glaucoma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642877/
https://www.ncbi.nlm.nih.gov/pubmed/29098083
http://dx.doi.org/10.1155/2017/2904272
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