Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients

BACKGROUND AND AIMS: Isoniazid (INH) is part of the first-line-therapy for tuberculosis (TB) but can cause drug-induced liver injury (DILI). Several candidate single nucleotide polymorphisms (SNPs) have been previously identified but the clinical utility of these SNPs in the prediction of INH-DILI r...

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Detalles Bibliográficos
Autores principales: Chan, Sze Ling, Chua, Angeline Poh Gek, Aminkeng, Folefac, Chee, Cynthia Bin Eng, Jin, Shengnan, Loh, Marie, Gan, Suay Hong, Wang, Yee Tang, Brunham, Liam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642896/
https://www.ncbi.nlm.nih.gov/pubmed/29036176
http://dx.doi.org/10.1371/journal.pone.0186200

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