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A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection

Introduction. Coronary artery stents are an uncommon site for infection. Only a handful of case reports describe this condition, and Staphylococcus aureus is the most frequent pathogen. Although rare, coronary stent infections are associated with a high mortality rate. Case presentation. We describe...

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Autores principales: Shafer, Krystle, Toma, Catalin, Galdys, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642999/
https://www.ncbi.nlm.nih.gov/pubmed/29114392
http://dx.doi.org/10.1099/jmmcr.0.005110
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author Shafer, Krystle
Toma, Catalin
Galdys, Alison
author_facet Shafer, Krystle
Toma, Catalin
Galdys, Alison
author_sort Shafer, Krystle
collection PubMed
description Introduction. Coronary artery stents are an uncommon site for infection. Only a handful of case reports describe this condition, and Staphylococcus aureus is the most frequent pathogen. Although rare, coronary stent infections are associated with a high mortality rate. Case presentation. We describe the case of a 50-year-old man with a past medical history of seven prior meticillin-resistant S. aureus (MRSA) infections over the previous 12 months, who presented with fever and was found to have persistent MRSA bacteraemia. During his hospital course, he developed chest pain and underwent coronary angiography, which revealed a left circumflex coronary to left atrium fistula, presumably due to endarteritis/sent infection. He was treated with combination parenteral antibiotics that were succeeded by oral suppressive therapy. Six months after his diagnosis of coronary stent infection, he suffered a fatal cardiac arrest. Conclusion. Coronary artery stents are an infrequent source of infection; when they occur, they are typically due to S. aureus, have a high mortality and ideally are treated with surgical intervention.
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spelling pubmed-56429992017-11-07 A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection Shafer, Krystle Toma, Catalin Galdys, Alison JMM Case Rep Case Report Introduction. Coronary artery stents are an uncommon site for infection. Only a handful of case reports describe this condition, and Staphylococcus aureus is the most frequent pathogen. Although rare, coronary stent infections are associated with a high mortality rate. Case presentation. We describe the case of a 50-year-old man with a past medical history of seven prior meticillin-resistant S. aureus (MRSA) infections over the previous 12 months, who presented with fever and was found to have persistent MRSA bacteraemia. During his hospital course, he developed chest pain and underwent coronary angiography, which revealed a left circumflex coronary to left atrium fistula, presumably due to endarteritis/sent infection. He was treated with combination parenteral antibiotics that were succeeded by oral suppressive therapy. Six months after his diagnosis of coronary stent infection, he suffered a fatal cardiac arrest. Conclusion. Coronary artery stents are an infrequent source of infection; when they occur, they are typically due to S. aureus, have a high mortality and ideally are treated with surgical intervention. Microbiology Society 2017-09-25 /pmc/articles/PMC5642999/ /pubmed/29114392 http://dx.doi.org/10.1099/jmmcr.0.005110 Text en 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Shafer, Krystle
Toma, Catalin
Galdys, Alison
A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title_full A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title_fullStr A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title_full_unstemmed A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title_short A common pathogen in an uncommon site: coronary artery stent meticillin-resistant Staphylococcus aureus infection
title_sort common pathogen in an uncommon site: coronary artery stent meticillin-resistant staphylococcus aureus infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642999/
https://www.ncbi.nlm.nih.gov/pubmed/29114392
http://dx.doi.org/10.1099/jmmcr.0.005110
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