The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma

Promoter methylation is the most significant mechanism to regulate O(6)-methylguanine-DNA-methyltransferase (MGMT) expression. Single-nucleotide polymorphisms (SNPs) in the MGMT promoter region may also play a role. The aim of this study was to evaluate the clinical significance of SNPs in the MGMT...

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Detalles Bibliográficos
Autores principales: Hsu, Chih-Yi, Ho, Hsiang-Ling, Lin, Shih-Chieh, Ho, Tiffany Dai-Hwa, Ho, Donald Ming-Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643071/
https://www.ncbi.nlm.nih.gov/pubmed/29036186
http://dx.doi.org/10.1371/journal.pone.0186430

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