Inhibition of CUG-binding protein 1 and activation of caspases are critically involved in piperazine derivative BK10007S induced apoptosis in hepatocellular carcinoma cells

Though piperazine derivative BK10007S was known to induce apoptosis in pancreatic cancer xenograft model as a T-type CaV3.1 a1G isoform calcium channel blocker, its underlying antitumor mechanism still remains unclear so far. Thus, in the present study, the antitumor mechanism of BK10007S was elucid...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Ha, Kwon, Hee Young, Ryu, Dong Hoon, Nam, Min-Ho, Shim, Bum Sang, Kim, Jin Han, Lee, Jae Yeol, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643113/
https://www.ncbi.nlm.nih.gov/pubmed/29036189
http://dx.doi.org/10.1371/journal.pone.0186490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643113/
https://www.ncbi.nlm.nih.gov/pubmed/29036189
http://dx.doi.org/10.1371/journal.pone.0186490

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