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Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice

C1 esterase inhibitor (C1-INH) can inhibit multiple pathways (complement, contact-kinin, coagulation, and fibrinolysis) that are all implicated in the pathophysiology of asthma. We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in a house dust mite (HDM) induced ast...

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Detalles Bibliográficos
Autores principales: Stroo, Ingrid, Yang, Jack, Anas, Adam A., de Boer, J. Daan, van Mierlo, Gerard, Roem, Dorina, Wouters, Diana, Engel, Ruchira, Roelofs, Joris J. T. H., van ‘t Veer, Cornelis, van der Poll, Tom, Zeerleder, Sacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643136/
https://www.ncbi.nlm.nih.gov/pubmed/29036225
http://dx.doi.org/10.1371/journal.pone.0186652