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Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice
C1 esterase inhibitor (C1-INH) can inhibit multiple pathways (complement, contact-kinin, coagulation, and fibrinolysis) that are all implicated in the pathophysiology of asthma. We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in a house dust mite (HDM) induced ast...
Autores principales: | Stroo, Ingrid, Yang, Jack, Anas, Adam A., de Boer, J. Daan, van Mierlo, Gerard, Roem, Dorina, Wouters, Diana, Engel, Ruchira, Roelofs, Joris J. T. H., van ‘t Veer, Cornelis, van der Poll, Tom, Zeerleder, Sacha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643136/ https://www.ncbi.nlm.nih.gov/pubmed/29036225 http://dx.doi.org/10.1371/journal.pone.0186652 |
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