Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos

The methylation of cytosine at CG sites in the mammalian genome is dynamically reprogrammed during gametogenesis and preimplantation development. It was previously shown that oocyte-derived DNMT1 (a maintenance methyltransferase) is essential for maintaining and propagating CG methylation at imprint...

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Detalles Bibliográficos
Autores principales: Maenohara, Shoji, Unoki, Motoko, Toh, Hidehiro, Ohishi, Hiroaki, Sharif, Jafar, Koseki, Haruhiko, Sasaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643148/
https://www.ncbi.nlm.nih.gov/pubmed/28976982
http://dx.doi.org/10.1371/journal.pgen.1007042

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