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PKCε phosphorylates MIIP and promotes colorectal cancer metastasis through inhibition of RelA deacetylation
EGFR signaling is implicated in NF-κB activation. However, the concrete mechanisms by which the core transducer of NF-κB signaling pathway, RelA/p65 is regulated under EGFR activation remains to be further clarified. Here, we show that EGF stimulation induces PKCε-dependent phosphorylation of migrat...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643311/ https://www.ncbi.nlm.nih.gov/pubmed/29038521 http://dx.doi.org/10.1038/s41467-017-01024-2 |