SRVF, a novel herbal formula including Scrophulariae Radix and Viticis Fructus, disrupts focal adhesion and causes detachment-induced apoptosis in malignant cancer cells

When cells lose adhesion, they undergo detachment-induced apoptosis, known as anoikis. In contrast, tumor cells acquire resistance to anoikis, enabling them to survive, even after separating from neighboring cells or the ECM. Therefore, agents that restore anoikis sensitivity may serve as anti-cance...

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Detalles Bibliográficos
Autores principales: Kim, Aeyung, Im, Minju, Ma, Jin Yeul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643381/
https://www.ncbi.nlm.nih.gov/pubmed/29038437
http://dx.doi.org/10.1038/s41598-017-12934-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643381/
https://www.ncbi.nlm.nih.gov/pubmed/29038437
http://dx.doi.org/10.1038/s41598-017-12934-y

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