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Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation
The molecular mechanisms underlying vascular inflammation and associated inflammatory vascular diseases are not well defined. Here we show that endothelial intracellular adenosine and its key regulator adenosine kinase (ADK) play important roles in vascular inflammation. Pro-inflammatory stimuli lea...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643397/ https://www.ncbi.nlm.nih.gov/pubmed/29038540 http://dx.doi.org/10.1038/s41467-017-00986-7 |